Romidepsin (FK-228)
| Overview | |
| Catalog # | bs-80492C |
| Product Name | Romidepsin (FK-228) |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:540.7 Formula:C24H36N4O6S2 Purity:>98% Solubility:Soluble in DMSO (up to 10 mg/ml). Chemical Name: |
| Description | A potent and selective inhibitor of class I histone deacetylases (HDACs), IC50 = 36, 47, 510 and 14,000 nM for HDAC1, 2, 4 and HDAC6, respectively1. Induces apoptosis in a variety of cell lines2 and displays antitumor activity in mouse models3. Recently approved for clinical use in T-cell lymphoma4. |
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