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TPCK

Overview
Catalog # bs-80471C
Product Name TPCK
Specifications
Storage Buffer powder
Storage Condition -20°C
Target
Product Information Molecular Weight:351.80

Formula:C17H18ClNO3S

Purity:>98%

Solubility:Soluble in DMSO (up to 10 mg/ml).

Chemical Name:N-p-Tosyl-L-phenylalanine chloromethyl ketone

Description TPCK is an irreversible inhibitor of the serine protease chymotrypsin.1 It also inhibits certain cysteine proteases (bromelain, ficin, papain).1 TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle.2