Hinokitiol

Overview
Catalog #	bs-80450C
Product Name	Hinokitiol
Specifications
Storage Buffer	powder
Storage Condition	RT
Target
Product Information	Molecular Weight:164.20 Formula:C10H12O2 Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). Chemical Name:β-Thujaplicin, 2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one
Description	Monoterpene natural product first isolated from the western red cedar1, identified as a metal chelator and ionophore with activity against microbial growth2,3. Inhibits mushroom tyrosinase (IC50 diphonolase activity = 0.21 μM)3 and platelet 12-lipoxygenase (IC50 = 100 nM)4. Protects against prion-induced neurotoxicity by inducing autophagy via HIF-1α activation. Causes G1 arrest, autophagy, and EGF-induced migration in HeLa cells6.