Ansamitocin P3
| Overview | |
| Catalog # | bs-80447C |
| Product Name | Ansamitocin P3 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:635.16 Formula:C32H43ClN2O9 Purity:>90% Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 30 mg/ml with warming). Chemical Name: |
| Description | Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin1,2. Ansamitocin P3 is a maytansine analog which displays potent cytotoxicity against various human tumor cell lines2,3. Maytansine and its analogs cause extensive disassembly of microtubules and totally prevent tubulin spiralization4. |
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