Gambogic acid
| Overview | |
| Catalog # | bs-80445C |
| Product Name | Gambogic acid |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:628.75 Formula:C38H44O8 Purity:>98% Solubility:Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 50 mg/ml) Chemical Name: |
| Description | Induces apoptosis in a variety of cell lines acting as an antagonist of Bcl-2 family proteins (IC50 < 1 μM)1, however additional targets may contribute to its cytotoxicity. It suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition.2 Potentiates the chemosensitivity of cancer cells to other agents.3 Down-regulates surviving, reversing docetaxel resistance in cancer cells.4 |
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