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Fasudil HCl

Overview
Catalog # bs-80425C
Product Name Fasudil HCl
Specifications
Storage Buffer powder
Storage Condition RT
Target
Product Information Molecular Weight:327.84

Formula:C14H17N3O2S · HCl

Purity:>98%

Solubility:Soluble in DMSO (up to 75 mg/ml) or in Water (up to 100 mg/ml).

Chemical Name:1-(5-Isoquinolinesulfonyl)homopiperazine HCl

Description Rho-associated kinase inhibitor (IC50 = 1.9 µM and 10.7 µM for Rho-associated kinase II and Rho-associated kinase respectively)1. Inhibits other kinases including cyclic nucleotide-dependent protein kinases.1 Reduces tryptamine-evoked vasopressor responses.2 attenuates bleomycin-induced pulmonary fibrosis in a mouse model.3 Clinically useful vasodilator.