Thiostrepton

Overview
Catalog #	bs-80409C
Product Name	Thiostrepton
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:1664.91 Formula:C72H85N19O18S5 Purity:>98% Solubility:Soluble in DMSO (up to 15 mg/ml), or in Chloroform (up to 5 mg/ml). Chemical Name:Fermentation product from Streptomyces azureus
Description	Novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as the activity of initiation factor-1 (IF-2)1-2. Displays antitumor activity. Induces apoptosis and cell cycle arrest in various tumor cells via downregulation of FOXM1 expression3.