2',3'-cGAMP
| Overview | |
| Catalog # | bs-80366C |
| Product Name | 2',3'-cGAMP |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:718.38 Formula:C20H22N10O13P2·2Na Purity:>98% Solubility:Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to 10 mg/ml) Chemical Name:Adenylyl-(3’5’)-2’guanylic acid, cyclic nucleotide, disodium salt |
| Description | 2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2’,3’-cGAMP which stimulates an inflammatory response.5 |
Powered by Bioz