DC260126

Overview
Catalog #	bs-80322C
Product Name	DC260126
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:307.37 Formula:C16H18NO2S Purity:>98% Solubility:Soluble in DMSO (up to 80 mg/ml) or in Ethanol (up to 80 mg/ml). Chemical Name:N-(4-Butylphenyl)-4-fluorobenzenesulfonamide
Description	A GPR40 receptor antagonist1. Suppresses fatty acid-induced elevation of intracellular Ca++. Inhibits palmitic acid potentiated glucose–stimulated insulin secretion in Min6 pancreatic β cells in vitro. Lowers serum insulin levels, increases insulin sensitivity2 in obese Zucker rats (6 mg/kg)2. Reduces pancreatic β cell apoptosis in obese diabetic (db/db) rats3. Protects Min6 β cells from palmitic acid-induced ER stress and apoptosis4