HIF-2a-I2
| Overview | |
| Catalog # | bs-80304C |
| Product Name | HIF-2a-I2 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:308.65 Formula:C12H6ClFN4O3 Purity:>98% Solubility:Soluble in DMSO (up to 30 mg/ml) or in DMF (up to 35 mg/ml) Chemical Name:N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine |
| Description | Potent and selective HIF-2α inhibitor, Kd=81 nM.1 Binds to the HIF-2α PAS-B domain2 and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2 |
Powered by Bioz