NKY-80

Overview
Catalog #	bs-80287C
Product Name	NKY-80
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:229.24 Formula:C12H11N3O2 Purity:>98% Solubility:Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming). Chemical Name:2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quainazolinone
Description	Potent and selective adenylyl cyclase inhibitor. Selective for AC5 over AC3 and AC2 (IC50 = 8.3 μM, 132 μM and 1.7 mM respectively)1,2. More recently shown to indiscriminately inhibit AC63. An extremely useful tool for probing the involvement of adenylyl cyclases in cellular signaling4.