ABT-418 HCl
| Overview | |
| Catalog # | bs-80279C |
| Product Name | ABT-418 HCl |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:202.68 Formula:C9H14N2O HCl Purity:>98% Solubility:Soluble in Water (up to 15 mg/ml) Chemical Name:3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole hydrochloride |
| Description | Agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC50= approximately 6 and 11 μM, respectively).1 Displays anxiolytic activity in a rat model and was 6-fold more potent than diazepam.2 Reduces distractibility in a primate model3 and may have relevance in attention deficit hyperactivity disorder4. Improves cognition in Alzheimer’s disease patients.5 |
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