LH-846
| Overview | |
| Catalog # | bs-80275C |
| Product Name | LH-846 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | RT |
| Target | |
| Product Information | Molecular Weight:316.81 Formula:C16H13ClN2OS Purity:>98% Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml with warming). Chemical Name:N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneaceramide |
| Description | Potent and selective inhibitor of casein kinase (CK) 1δ., IC50s=0.29, 1.3 and 2.5 μM for δ, ε and α isoforms respectively with no inhibition of CK2. Inhibits CK1δ-mediated phosphorylation and degradation of PER1 protein and lengthens circadian period in U2OS cells.1 |
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