NSC632839

Overview
Catalog #	bs-80225C
Product Name	NSC632839
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:339.86 Formula:C21H21NO · HCl Purity:>98% Solubility:Soluble in DMSO (up to 8 mg/ml). Chemical Name:3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
Description	A pan-specific ubiquitin isopeptidase inhibitor. (IC50= 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively) Does not effect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway1,2. Cell permeable.