AG-1517 HCl
| Overview | |
| Catalog # | bs-80221C |
| Product Name | AG-1517 HCl |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | RT |
| Target | |
| Product Information | Molecular Weight:360.21 Formula:C16H14BrN3O2 Purity:>98% Solubility:Soluble in DMSO (up to 5 mg/ml). Chemical Name:4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride |
| Description | An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3. |
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