Aristolochic acid (A&B)
| Overview | |
| Catalog # | bs-80198C |
| Product Name | Aristolochic acid (A&B) |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | RT |
| Target | |
| Product Information | Molecular Weight:341.3 and 311.3 Formula:C17H11NO7 and C16H9NO6 Purity:>98% Solubility:Soluble in DMSO (up to 30 mg/ml) Chemical Name:8-Methoxy-6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (A) and 6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid (B) |
| Description | Phytochemical that acts as an anti-inflammatory and phospholipase A2 (PLA2) inhibitor (IC50 = 40 µM in human neutrophils)1. Its mutagenic properties cause tumorigenesis and kidney damage in rodent models and in humans2,3. Induces NF-κB, TGF-β, and oxidative stress in mouse kidney, and mitochondrial apoptosis in rat liver4,5. |
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