24(S)-hydroxycholesterol
| Overview | |
| Catalog # | bs-80191C |
| Product Name | 24(S)-hydroxycholesterol |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:402.7 Formula:C27H46O2 Purity:>98% Solubility:Soluble in DMSO (up to 10 mg/ml with warming) or in Ethanol (up to 10 mg/ml). Chemical Name:Cholest-5-ene-3β,24S-diol |
| Description | Metabolite of cholesterol produced in the brain by the action of CYP46A1 thereby regulating brain cholesterol homeostasis1. Endogenous agonist for the nuclear receptor LXR2. Cerebrospinal fluid content of 24(S)-hydroxycholesterol is reduced in Alzheimer’s disease patients3. Induces RIPK1-dependent necrosis-like cell death in the absence of caspase-84. |
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