IWP-2

Overview
Catalog #	bs-80178C
Product Name	IWP-2
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:466.61 Formula:C22H18N4O2S3 Purity:>98% Solubility:Soluble in DMSO (up to 5 mg/ml, with warming). Chemical Name:N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Description	IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50=27nM) by inhibition of the O-acyltransferase Porcn1. Induces cardiomyocyte differentiation from human pluripotent stem cells2. An important tool to probe the involvement of the Wnt pathway in physiological processes3,4. Cell permeable.