LDN-57444

Overview
Catalog #	bs-80175C
Product Name	LDN-57444
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:397.65 Formula:C17H11Cl3N2O3 Purity:>98% Solubility:Soluble in DMSO (up to 20 mg/ml). Chemical Name:5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)
Description	Inhibits ubiquitin C-terminal hydrolase (UCH-L1) (Ki=0.4 M). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Cell permeable.