New to Bioss? Enjoy 35% of your first order. Use code "FirstOrder35" - Offer valid for new U.S. Customers on direct orders only

IU1

Overview
Catalog # bs-80131C
Product Name IU1
Specifications
Storage Buffer powder
Storage Condition -20°C
Target
Product Information Molecular Weight:300.38

Formula:C18H21FN2O

Purity:>98%

Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml).

Chemical Name:1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone

Description Selective inhibitor of Usp14 (IC50<4 μM). Enhances proteasome activity and substrate proteolysis.1,2 Inhibits Dengue virus replication.3 In prion-infected CAD5 cells activation of the ubiquitin proteasome system by IU1 is sufficient to induce clearance of polyubiquitinated substrates and reduce misfolded prion protein load.4 Attenuates ischemia/reperfusion-induced neuronal injury in a mouse model.5 Cell permeable.