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WHI-P131

Overview
Catalog # bs-80124C
Product Name WHI-P131
Specifications
Storage Buffer powder
Storage Condition -20°C
Target
Product Information Molecular Weight:333.78

Formula:C16H15N3O3 · HCl

Purity:>98%

Solubility:Soluble in DMSO (up to 50 mg/ml).

Chemical Name:4-[(4’-hydroxyphenyl)amino]-6,7-dimehtoxyquinazoline

Description JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion.1 Increases survival in a mouse ALS model.2 Delays or prevents autoimmune type 1 diabetes in NOD mice.3 Exhibits potent anti-inflammatory activity in mouse models of peritonitis, colitis, cellulitis and systemic inflammatory response syndrome.4 Displays protective effects against myocardial ischemia and reperfusion injury in mouse models.5