7,8-Dihydroxyflavone
| Overview | |
| Catalog # | bs-80115C |
| Product Name | 7,8-Dihydroxyflavone |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:254.25 Formula:C15H10O4 Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 6 mg/ml). Chemical Name:7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one |
| Description | A selective TrkB agonist (Kd=320 nM) with potent neurotrophic activity.1,2 Significantly improves motor deficits, ameliorates brain atrophy and extends survival in the well-characterized N171-82Q Huntington’s disease mouse model.3 Post-traumatic brain injury-treatment promotes neurogenesis in the hippocampus in a mouse model.4 Improves motor performance and motor neuronal survival in an ALS mouse model.5 |
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