Retinoic acid

Overview
Catalog #	bs-80089C
Product Name	Retinoic acid
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:300.44 Formula:C20H28O2 Purity:>98% Solubility:Soluble in DMSO (up to 8 mg/ml) or in Ethanol (up to 15 mg/ml). Chemical Name:3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Description	all−trans−Retinoic acid (ATRA; a metabolite of Vitamin A) is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 ATRA promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4