Galanthamine HBr
| Overview | |
| Catalog # | bs-80088C |
| Product Name | Galanthamine HBr |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:368.27 Formula:C17H21NO3 · HBr Purity:>97% Solubility:Soluble in DMSO (up to 10 mg/ml) or in Water (up to 12 mg/ml). Chemical Name:4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol, hydrobromide |
| Description | Long-acting, centrally active acetylcholinesterase inhibitor, IC50 = 410 nM1. Allosteric potentiator at neuronal nicotinic ACh receptors2. Prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells3. Clinically useful agent for symptomatic relief of Alzheimer’s disease but fails to prevent progression of the disease4,5. |
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