EX-527
Overview | |
Catalog # | bs-80055C |
Product Name | EX-527 |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:248.71 Formula:C13H13ClN2O Purity:>98% Solubility:Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml). Chemical Name:6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic) |
Description | Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable. |