A-803467
Overview | |
Catalog # | bs-80044C |
Product Name | A-803467 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:357.80 Formula:C19H16ClNO4 Purity:>98% Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 2 mg/ml). Chemical Name:5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide |
Description | Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50's for rat and human Nav1.8 are 140 nM and 8.0 nM respectively. |