Aluminon

Overview
Catalog #	bs-75861c-25g
Product Name	Aluminon
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at RT.
Target
Product Information	CAS Number: 569-58-4 Molecular formula: C22H14O9 . 3NH3 Molecular weight: 422.3 . 51.1 Purity: n.a. Appearance: Dark red to brown powder. Solubility: Soluble in DMSO or water (50mg/ml). InChiKey: AIPNSHNRCQOTRI-UHFFFAOYSA-N SMILES: OC1=CC=C(/C(C2=CC=C(O)C(C([O-])=O)=C2)=C3C=C(C([O-])=O)C(C=C/3)=O)C=C1C([O-])=O.[NH4+].[NH4+].[NH4+]
Description	Aluminon, the triammonium salt of aurintricarboxylic acid, is a dye commonly used to detect the presence of the aluminium ion in an aqueous solution. In addition to its use in qualitative inorganic analysis, aluminon has applications in pigment production. It forms brilliantly colored lake pigments with aluminum, chromium, iron and beryllium. Spectral data: AL-Complex Absorbance at ~525nm. Aurintricarboxylic acid readily polymerizes in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of RNA-directed DNA polymerase and topoisomerase II. Angiogenesis inhibitor. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. It is neuroprotective maybe due to calpain inhibition. It has antiviral properties, is a potent phosphofructokinase inhibitor, a TWEAK-Fn14 signaling pathway inhibitor and a DNMT1 inhibitor.