Geldanamycin

Overview
Catalog #	bs-75700c-100ug
Product Name	Geldanamycin
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Target
Product Information	CAS Number: 30562-34-6 Molecular formula: C29H40N2O9 Molecular weight: 560.6 Purity: >98% (HPLC) Appearance: Yellow solid. Solubility: Soluble in methanol or DMSO; insoluble in water. InChiKey: QTQAWLPCGQOSGP-GAEFGYQESA-N SMILES: CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)C2=O
Description	Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor.