Rebeccamycin

Overview
Catalog #	bs-75690c-1mg
Product Name	Rebeccamycin
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 1 year after receipt when stored at -20°C. Stock solutions are stable for 3 months when stored at -20°C. After reconstitution, prepare aliquots and store at -20°C.
Target
Product Information	CAS Number: 93908-02-2 Molecular formula: C27H21Cl2N3O7 Molecular weight: 570.4 Purity: >98% (HPLC) Appearance: Yellow solid. Solubility: Soluble in DMSO. InChiKey: QEHOIJJIZXRMAN-UMHCKEELSA-N SMILES: COC1C(O)C(O)C(OC1CO)N1C2=C3NC4=C(C=CC=C4Cl)C3=C3C(=O)NC(=O)C3=C2C2=C1C(Cl)=CC=C2
Description	Antibiotic. Structurally similar to staurosporine. Selective activity against several cancer cell lines. DNA intercalator, resulting in catalytic inhibition of topoisomerases I. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells). Does not show any inhibitory activity against protein kinases.