Mensacarcin

Overview
Catalog #	bs-75663c-1mg
Product Name	Mensacarcin
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Target
Product Information	CAS Number: 808750-39-2 Molecular formula: C21H24O9 Molecular weight: 420.4 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO or methanol. InChiKey: WWNXYRCJJRRWAQ-UJLZTCEPSA-N SMILES: CO[C@H]1C2=C(OC)C=CC=C2C(=O)[C@@]23O[C@@]12[C@@H](O)[C@@](O)([C@@H](C)[C@H]3O)C(=O)[C@@H]1O[C@H]1C
Description	Antibiotic. Cytotoxic. Antitumor compound. Anti-melanoma drug lead compound. Effective in BRAF V600E mutation cell lines. Potently induces apoptosis in melanoma cells. Localizes to mitochondria, affects energy metabolism in mitochondria rapidly and activates caspase-3/7-dependent apoptotic pathways. Inhibits cell growth in a borad range of human cancer cell lines. Shows cell type specificity inducing strong cytostasis most effective in cancer types with low oxygen respiration ratios like melanomas.