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Elbasvir

Overview
Catalog # bs-75610c-1mg
Product Name Elbasvir
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 1370468-36-2

Molecular formula: C49H55N9O7

Molecular weight: 882

Purity: >98% (HPLC)

Appearance: White to off-white solid.

Solubility: Soluble in DMSO (20mg/ml), DMF (25mg/ml) or ethanol (25mg/ml).

InChiKey: BVAZQCUMNICBAQ-ISSDNXAZSA-N

SMILES: O=C(N1CCCC1C2=NC=C(C3=CC4=C(N(C5=C4)[C@@H](OC6=C5C=CC(C7=CN=C(N7)[C@@H]8CCCN8C([C@H](C(C)C)NC(OC)=O)=O)=C6)C9=CC=CC=C9)C=C3)N2)[C@@H](NC(OC)=O)C(C)C
Description Elbasvir is a direct-acting antiviral drug that potently inhibits hepatitis C virus (HCV) non-structural protein 5A (NS5A). NS5A is essential for HCV RNA synthesis and viral assembly, and elbasvir inhibits the assembly of new viral replicase complexes when used at a concentration of 50 pM. It exhibits potent inhibitory activity against a broad range of HCV genotypes. Formulations containing elbasvir have been used alone and in combination with NS3/4A protease inhibitors in the treatment of HCV. Identified as a potential inhibitor of SARS-CoV-2, responsible for COVID-19.