Oseltamivir . phosphate salt

Overview
Catalog #	bs-75595c-25mg
Product Name	Oseltamivir . phosphate salt
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 204255-11-8 Molecular formula: C16H28N2O4 . H3PO4 Molecular weight: 312.4 . 98.0 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO (10mg/ml) or water (10mg/ml). InChiKey: POPJIXMLXGJJOV-ZFSDTUNKSA-N SMILES: O=P(OO)=O.N[C@@H]1[C@@H](NC(C)=O)[C@H](OC(CC)CC)C=C(C(OCC)=O)C1.[HH]
Description	Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. It is an antiviral prodrug targeted against the influenza viruses. Once hydrolyzed in the liver to its active metabolite, oseltamivir carboxylate, it can competitively inhibit viral neuraminidase (IC50s=0.1-4.9nM for influenza neuraminidases A and B). The enzyme cleaves the sialic acid which is found on glycoproteins on the surface of human cells that helps new virions to exit the cell. Thus oseltamivir is blocking the release of new viral particles from a host cell. Oseltamivir phosphate is used clinically to treat influenza A and influenza B and to prevent flu after exposure. It potentially could be used to reduce the spread of the SARS-CoV-2 and counteract against the transmission of COVID-19.