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3-Bromopyruvic acid

Overview
Catalog # bs-75570c-1g
Product Name 3-Bromopyruvic acid
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 1113-59-3

Molecular formula: C3H3BrO3

Molecular weight: 167

Purity: >98%

Appearance: White to off-white solid.

Solubility: Soluble in water (50mg/ml).

InChiKey: PRRZDZJYSJLDBS-UHFFFAOYSA-N

SMILES: O=C(CBr)C(O)=O
Description Cell permeable pyruvic acid derivative. Hexokinase II (HK2) inhibitor. Useful agent for immunometabolism research. Antitumor agent. Inhibits the rate limiting step of glycolysis and effectively suppress tumor survival in vitro and in vivo. Displays potent cytotoxic activity against cancer cells with mitochondrial respiratory defects and cells in hypoxic environment. Antifungal agent (anticryptococcal). Also used as affinity label for cysteine residues and cross-linker between nucleic acids and proteins.