ID-8

Overview
Catalog #	bs-75547c-1mg
Product Name	ID-8
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 147591-46-6 Molecular formula: C16H14N2O4 Molecular weight: 298.3 Purity: >98% (1H-NMR) Appearance: Solid. Solubility: Soluble in DMSO (25mg/ml) and DMF (30mg/ml). InChiKey: VVZNWYXIOADGSW-UHFFFAOYSA-N SMILES: CC1=C([N+]([O-])=O)C2=CC=C(O)C=C2N1C3=CC=C(OC)C=C3
Description	Cell culture supplement that can sustain self-renewal and pluripotency of mouse embryonic stem cells (ESCs) in vitro. At 10µM it stimulates proliferation in serum-free media at a steady rate for more than 30 days. Reversibly maintains the long-term culture of ESCs by sustaining Nanog gene expression through Sox2-Oct3/4 activation and enhances Wnt-mediated hESC survival and proliferation via inhibition of DYRKs (DYRK2 and DYRK4).