Regorafenib [BAY 73-4506]
| Overview | |
| Catalog # | bs-75522c-5mg |
| Product Name | Regorafenib [BAY 73-4506] |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 755037-03-7 Molecular formula: C21H15ClF4N4O3 Molecular weight: 482.8 Purity: >98% (HPLC) Appearance: Light pink to white solid. Solubility: Soluble in DMSO (>50mg/ml). Slightly soluble in ethanol (1mg/ml). Insoluble in water. InChiKey: FNHKPVJBJVTLMP-UHFFFAOYSA-N SMILES: CNC(=O)C1=CC(OC2=CC(F)=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)=CC=N1 |
| Description | Orally bioavailable potent antitumor, antiangiogenic, antiproliferative and antineoplastic agent. Multi-target kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, Kit, RET and Raf-1 with IC50 values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively. |
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