Auranofin

Overview
Catalog #	bs-75513c-25mg
Product Name	Auranofin
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at +20°C.
Target
Product Information	CAS Number: 34031-32-8 Molecular formula: C20H34AuO9PS Molecular weight: 678.5 Purity: >95% Appearance: White to off-white solid. Solubility: Soluble in DMSO or 100% ethanol. Insoluble in water. InChiKey: AUJRCFUBUPVWSZ-XTZHGVARSA-M SMILES: CCP(CC)(CC)=[Au]SC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
Description	Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway. Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5. Potent thioredoxin reductase (TrxR) inhibitor. Induces mitochondrial membrane permeability transition. Anti-cancer compound with anti-proliferative activity. Shown to induce apoptosis and necrosis. STAT3 and telomerase activity inhibitor. Proteasomal deubiquitinase inhibitor. Antibiotic, antiviral and antiparasitic compound. Immunosuppressive.