Finasteride

Overview
Catalog #	bs-75498c-25mg
Product Name	Finasteride
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 98319-26-7 Molecular formula: C23H36N2O2 Molecular weight: 372.5 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO, DMF, ethanol or methanol. Sparingly soluble in water. InChiKey: DBEPLOCGEIEOCV-WSBQPABSSA-N SMILES: [H][C@@]12CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])NC(=O)C=C[C@]12C
Description	Potent, specific and competitive inhibitor of type II 5alpha-reductase (enzyme which converts testosterone to the more potent 5alpha-dihydrotestosterone) [1, 3]. Anticancer compound [2, 6, 7]. Apoptosis modulator [2, 6]. Enhances the action of GABA at GABA(A) receptors, which leads to neurological implications [4]. Inhibit testosterone-induced type I procollagen and TGF-beta1 expression in human scalp dermal fibroblasts in a model of androgenic alopecia [5]. Drug for the treatment of male androgenetic alopecia [8]. Potential role in neuropsychiatric disorders [9]. Shown to reduce L-DOPA-induced dyskinesia in rodent models for Parkinson’s disease [10].