Gardiquimod

Overview
Catalog #	bs-75492c-5mg
Product Name	Gardiquimod
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C. Stock solutions are stable for 3 months when stored at -20°C.
Target
Product Information	CAS Number: 1020412-43-4 Molecular formula: C17H23N5O Molecular weight: 313.4 Purity: >98% Appearance: White to off-white powder. Solubility: Soluble in DMSO (30mg/ml), dioxane (5mg/ml), methanol (30mg/ml) or acetonitrile (2mg/ml). InChiKey: FHJATBIERQTCTN-DZQCGVKKCV SMILES: CCNCC1=NC2=C(N1CC(C)(C)O)C1=C(C=CC=C1)N=C2N
Description	Immune response modifier. Antiviral and antitumor compound Selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0.1µg/ml. 10 times more active than Imiquimod (Prod. No. bs-75480C). At high concentrations (3µg/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines.