Imiquimod

Overview
Catalog #	bs-75480c-100mg
Product Name	Imiquimod
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C. Stock solutions are stable for 3 months when stored at -20°C.
Target
Product Information	CAS Number: 99011-02-6 Molecular formula: C14H16N4 Molecular weight: 240.3 Purity: >98% Appearance: White to off-white powder. Solubility: Soluble in DMSO or dimethylformamide. Insoluble in ethanol. Slightly soluble in water. InChiKey: DOUYETYNHWVLEO-UHFFFAOYSA-N SMILES: CC(C)CN1C=NC2=C1C1=CC=CC=C1N=C2N
Description	Immune response modulator [1, 2]. Anti-inflammatory [3, 5]. TLR7 agonist [3, 5]. Stimulates proinflammatory cytokine production interferon-alpha (IFN-alpha), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) and activates NF-kappaB [3, 5]. Caspase-3 activator that directly induces procaspase-3 cleavage [4]. Anti-cancer compound [4, 9]. Apoptosis inducer [4, 9]. Antiproliferative, independent of immune system activation or function. Antiviral [10] and anti-angiogenic [6, 7, 8]. Approved treatment for external genital warts caused by human papillomavirus infection [10].