GANT61

Overview
Catalog #	bs-75473c-1mg
Product Name	GANT61
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 500579-04-4 Molecular formula: C27H35N5 Molecular weight: 429.6 Purity: >98% Appearance: White to off-white solid. Solubility: Soluble in DMSO or ethanol. InChiKey: KVQOGDQTWWCZFX-UHFFFAOYSA-N SMILES: CN(C)C1=CC=CC=C1CN1CCCN(CC2=C(C=CC=C2)N(C)C)C1C1=CC=NC=C1
Description	Cell permeable GLI antagonist. Inhibits Gli1 and Gli2-induced transcription [1]. Sonic hedgehog (Shh) signaling pathway inhibitor, downstream of SMO and SUFU [1]. Displays antiproliferative and antitumor activity in vitro and in vivo [1, 2 , 3, 4, 5]. Apoptosis inducer [1, 2 , 3, 4, 5].