6-ECDCA

Overview
Catalog #	bs-75472c-5mg
Product Name	6-ECDCA
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 459789-99-2 Molecular formula: C26H44O4 Molecular weight: 420.6 Purity: >95% (NMR) Appearance: White solid. Solubility: Soluble in ethanol, methanol, or DMSO. Slightly soluble in water, dichloromethane and acetone. InChiKey: ZXERDUOLZKYMJM-AMGBFIHRSA-N SMILES: [H][C@@]12C[C@H](O)CC[C@]1(C)C1CC[C@]3(C)[C@H](CCC3C1[C@H](O)[C@@H]2CC)[C@H](C)CCC(O)=O
Description	Potent and selective farnesoid X receptor FXR agonist (EC50= 99nM) [1]. Induces SHP in HSCs to suppress TIMP-1 expression [2]. Apoptosis inducer [2]. Protects against liver fibrosis development in rat in vivo [2]. Displays anticholeretic activity in rat in vivo [3]. Promotes preadipocyte differentiation [4]. Regulates adipogenesis and insulin signaling in vivo [4]. Inhibits vascular smooth muscle cell inflammation and migration [5].