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SANT-2

Overview
Catalog # bs-75439c-1mg
Product Name SANT-2
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Target
Product Information CAS Number: 329196-48-7

Molecular formula: C26H26ClN3O4

Molecular weight: 480

Purity: >95% (NMR)

Appearance: White to off-white solid.

Solubility: Soluble in DMSO, ethanol or chloroform.

InChiKey: VQOJFGFKIVFMDH-UHFFFAOYSA-N

SMILES: CCOC1=CC(=CC(OCC)=C1OCC)C(=O)NC1=CC(C2=NC3=C(N2)C=CC=C3)=C(Cl)C=C1
Description Sonic hedgehog (Shh) signaling pathway modulator. Cell permeable potent smoothened (Smo) antagonist. Inhibits wt and oncogenic Smo. SAG activity (Prod. Nr. AG-CR1-3506) inhibitor. Gli1 reporter gene expression inhibitor. Suppresses the Shh-dependent translocation of Smo to the primary cilium. Potential tumor growth blocker.