SANT-2
Overview | |
Catalog # | bs-75439c-1mg |
Product Name | SANT-2 |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
Target | |
Product Information | CAS Number: 329196-48-7 Molecular formula: C26H26ClN3O4 Molecular weight: 480 Purity: >95% (NMR) Appearance: White to off-white solid. Solubility: Soluble in DMSO, ethanol or chloroform. InChiKey: VQOJFGFKIVFMDH-UHFFFAOYSA-N SMILES: CCOC1=CC(=CC(OCC)=C1OCC)C(=O)NC1=CC(C2=NC3=C(N2)C=CC=C3)=C(Cl)C=C1 |
Description | Sonic hedgehog (Shh) signaling pathway modulator. Cell permeable potent smoothened (Smo) antagonist. Inhibits wt and oncogenic Smo. SAG activity (Prod. Nr. AG-CR1-3506) inhibitor. Gli1 reporter gene expression inhibitor. Suppresses the Shh-dependent translocation of Smo to the primary cilium. Potential tumor growth blocker. |