KBU2046

Overview
Catalog #	bs-75416c-1mg
Product Name	KBU2046
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 1143863-69-7 Molecular formula: C15H11FO2 Molecular weight: 242.2 Purity: >98% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in DMSO, ethanol, methanol or DCM. Insoluble in water. InChiKey: XKAFGKFIJBGYAP-UHFFFAOYSA-N SMILES: O=C1C(C2=CC=C(F)C=C2)COC3=CC=CC=C31
Description	Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.