Compound 112254

Overview
Catalog #	bs-75413c-10mg
Product Name	Compound 112254
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 949745-75-9 Molecular formula: C26H35N3O3 Molecular weight: 437.6 Purity: >98% (NMR) Appearance: White crystalline solid. Solubility: Soluble in DMSO, 100% ethanol, methanol or dichloromethane. Insoluble in water. InChiKey: XBEMZEZVTNPLQI-UHFFFAOYSA-N SMILES: COC1=CC=C(CN2CCN(CC2)C(=O)CCNC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1
Description	Adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Prod. No. bs-75412C) [1, 2]. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells [1]. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms [1].