PD 98,059
| Overview | |
| Catalog # | bs-75405c-1mg |
| Product Name | PD 98,059 |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Target | |
| Product Information | CAS Number: 167869-21-8 Molecular formula: C16H13NO3 Molecular weight: 267.3 Purity: >98% (NMR) Appearance: Yellow solid. Solubility: Soluble in anhydrous DMSO, methanol or dichloromethane. Slightly soluble in ethanol. InChiKey: QFWCYNPOPKQOKV-UHFFFAOYSA-N SMILES: COC1=C(N)C(=CC=C1)C1=CC(=O)C2=CC=CC=C2O1 |
| Description | Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor [1-3, 7]. Blocks the phosphorylation and activation of the MAP kinase pathway [1-3, 7]. T cell activation inhibitor [4]. Inhibits cell growth and cell proliferation of several cancer cells [5, 6, 8]. |
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