Nocodazole

Overview
Catalog #	bs-75353c-5mg
Product Name	Nocodazole
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 31430-18-9 Molecular formula: C14H11N3O3S Molecular weight: 301.3 Purity: >98% (NMR) Appearance: White to off-white solid. Solubility: Soluble in DMSO or dimethylformamide; almost insoluble in water. InChiKey: KYRVNWMVYQXFEU-UHFFFAOYSA-N SMILES: COC(=O)NC1=NC2=CC=C(C=C2N1)C(=O)C1=CC=CS1
Description	Microtubule inhibitor [1, 2, 4]. Antitumor compound [1, 2]. Mitosis inhibitor [3]. Arrests the cell cycle at G2/M phase [9]. Promotes tubulin depolymerization [4]. Induces fragmentation of the Golgi complex [5]. Inhibits the T cell antigen receptor [6]. Stimulates the intrinsic GTPase activity of tubulin [7]. Activates the JNK/SAPK signaling pathway [8]. Apoptosis inducer [10, 11]. Autophagy inhibition through prevention of autophagosome-lysosome fusion.