BAY 11-7082
| Overview | |
| Catalog # | bs-75348c-10mg |
| Product Name | BAY 11-7082 |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 19542-67-7 Molecular formula: C10H9NO2S Molecular weight: 207.3 Purity: >99% (NMR) Appearance: White to off-white crystalline solid. Solubility: Soluble in DMSO, 100% ethanol, dichloromethane or ethyl acetate; insoluble in water. InChiKey: DOEWDSDBFRHVAP-KRXBUXKQSA-N SMILES: CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)\C=C\C#N |
| Description | IkappaBalpha kinase inhibitor. NF-kappaB inhibitor. Potential anti-inflammatory agent. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. NLRP3 inflammasome inhibitor. Reduces ATPase activity of the NLRP3 inflammasome. Inhibits platelet aggregation. RBR E3 ligase inhibitor. Effects by inactivating the E2-conjugating enzymes Ubc13 and UbcH7 and the E3 ligase LUBAC, preventing the formation of Lys63-linked and linear polyubiquitin chains. |
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