H-89 . dihydrochloride

Overview
Catalog #	bs-75338c-1mg
Product Name	H-89 . dihydrochloride
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 130964-39-5; 127243-85-0 (free base) Molecular formula: C20H20BrN3O2S . 2HCl Molecular weight: 446.4 . 72.9 Purity: >98% (NMR) Appearance: White to off-white solid. Solubility: Soluble in DMSO (50mg/ml), DMF (20mg/ml), ethanol (1mg/ml) or methanol (1mg/ml). Slightly soluble in water. InChiKey: ZKZXNDJNWUTGDK-NSCUHMNNSA-N SMILES: BrC1=CC=C(C=CCNCCNS(=O)(=O)C2=C3C=CN=CC3=CC=C2)C=C1
Description	Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor [1-3]. Protein kinase Cµ (PKCµ) inhibitor [4]. Ca2+/calmodulin-dependent protein kinase II inhibitor [2]. Casein kinase I inhibitor [2]. Myosin light chain kinase (MLCK) inhibitor [2]. Apoptosis enhancer [5]. Tool to study protein crystal structure-inhibitor interactions [6]. Rho kinase inhibitor [7]. Cell proliferation inhibitor [8]. Review [9].