Antipain . dihydrochloride

Overview
Catalog #	bs-75330c-5mg
Product Name	Antipain . dihydrochloride
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 3 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 37682-72-7 Molecular formula: C27H44N10O6 . 2HCl Molecular weight: 604.7 . 72.9 Purity: >97% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in water, ethanol, methanol, DMSO or acetonitrile. InChiKey: YAHXZYICKJUJEO-BXLPLHKWSA-N SMILES: [Cl-].[Cl-].[H]C(=O)C(CCCNC(N)=[NH2+])NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)NC(CC1=CC=CC=C1)C(O)=O)C(C)C
Description	Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D. Similar activity spectrum comparable to leupeptin (AG-CP3-7000). Acts by forming a hemiacetal adduct between its aldehyde group and the active serine of the proteinase. Inhibits transformation of NIH3T3 cells after transfection with an activated H-ras oncogene. Used to evaluate the role of proteases in the process of malignant cell transformations. Shows antibacterial and antiparasitic activity.