Semaglutide

Overview
Catalog #	bs-75323c-1mg
Product Name	Semaglutide
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 1 year after receipt when stored at -20°C.
Target
Product Information	CAS Number: 910463-68-2 (parent) Molecular formula: C187H291N45O59 Molecular weight: 4113.6 Purity: >98% (HPLC) Appearance: White lyophilized powder. Solubility: Soluble in aqueous solution (5% AcOH) (1mg/ml). InChiKey: DLSWIYLPEUIQAV-CIIFZSTISA-N SMILES: CC(C(N[C@@H](CCC(O)=O)C(NCC(N[C@]([C@H](O)C)([H])C(N[C@H](C(N[C@]([C@H](O)C)([H])C(N[C@@H](CO)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@]([C@@H](C)CC)([H])C(N[C@H](C(N[C@H](C(N[C@@H]CC(C)C)C(N[C@@H]C(C)C)C(N[C@@H]CCCNC(N)=N)C(NCC(N[C@@H]CCCNC(N)=N)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)CC1=CNC2=C1C=CC=C2)=O)C)=O)=O)CC3=CC=CC=C3)=O)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@@H]C(O)=O)NC(CCCCCCCCCCCCCCCCC(O)=O)=O)=O)=O)=O)=O)C)=O)C)=O)=O)=O)=O)=O)CC(C=C4)=CC=C4O)=O)=O)=O)=O)CC(O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)(C)NC([C@@H](N[H])CC6=CN=CN6)=O
Description	Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner. Longer-acting alternative to liraglutide. Chemically similar to glucagon-like peptide-1 (GLP-1), with two amino acid substitutions compared to human GLP-1 (Aib(8), Arg(34)) and derivatized at lysine 26. Antiobesity activity. Reduces energy intake, likely mechanisms for semaglutide-induced weight loss include less appetite and food cravings, better control of eating and lower relative preference for fatty, energy-dense foods.